Venous leg ulcers occur when valves in the leg veins fail to return blood to the heart. Mild cases can often be treated with compression stockings, while skin grafting may be necessary for more severe cases. A spray consisting of keratinocyte and fibroblast skin cells has shown promising results in a study across the United States and Canada, successfully treating venous leg ulcers without requiring skin grafts. What are the specifics?
228 Patients, 5 Different Tests
The study followed 228 patients with no more than three venous leg ulcers. At random, these patients were placed into one of five groups: a placebo spray once every seven days, a mild dose of keratinocyte and fibroblast spray once every seven or fourteen days, or a stronger dose of keratinocyte and fibroblast spray once every seven or fourteen days. After twelve weeks, patients that received doses of fibroblast and keratinocyte saw noticeable improvement in their ulcers compared to those that only received the placebo spray. Even more interesting, and unexpected, the lowest dose of keratinocyte and fibroblast spray administered once every fourteen days showed the highest levels of healing.
No Promises Yet
So far, researchers are still pointing to compression stockings as the primary course of treatment for venous leg ulcers, as it helps with venous return and helps prevent venous pooling. The keratinocyte and fibroblast spray may, however, be considered for more severe venous leg ulcers. In addition, this spray may theoretically prove useful for diabetic and ischemic foot ulcers, although those studies are not underway as of yet.
Leg Veins Troubling You? Let Us Help You!
Leg vein abnormalities and other blood flow problems should never be ignored, as they may be indicative of a more serious condition. If you are experiencing any leg vein problems, contact us today to schedule a consultation. At Advanced Dermatology, PC, our board-certified dermatologists are experts at diagnosing and treating many different leg vein conditions. We do advanced studies to diagnose the problem and have the latest techniques to solve some of the most difficult cases, including CTEV. Our nine conveniently located offices welcome patients from Queens, Long Island (Roslyn/Albertson, West Islip, Commack, East Setauket), New York City, Bergen County, NJ, Union County, NJ, and all surrounding areas.